Sequence Bio GTM brain

Sequence Bio uses Newfoundland and Labrador population genetics to discover disease biology and work with life sciences partners on medicines.

category

Human genetics drug discovery

market profile

  • text: Genetic evidence can help discovery teams prioritize targets and understand treatment response.
  • text: The business combines research participants, clinical collaborators and life sciences partnerships; product and licensing revenue are not publicly specified.

personas

  • title: Pharma head of discovery genetics
    pains:
    • Prioritizing targets with insufficient human causal evidence
    • Finding differentiated genetic signals for hard-to-treat diseases
  • title: Biopharma business development director
    pains:
    • Finding differentiated external disease biology
    • Structuring research collaborations that can advance into medicines
  • title: Clinical and academic genetics investigator
    pains:
    • Recruiting families with inherited disease
    • Connecting family and clinical histories to genetic insights

icp

  • text: Life sciences organizations pursuing genetically informed target discovery and therapeutic development; size and geography are not specified.
  • text: Newfoundland and Labrador clinical providers and academic research groups studying inherited disease are research partners.

message pillars

  • text: Ground better medicines in human genetics.
  • text: Use the founder population to focus on genetic disease drivers.
  • text: Pair local clinical expertise with life sciences partners.

objections

  • objection: Will findings from a founder population generalize?
    response: Review each target's human evidence and a replication plan with the scientists.
  • objection: How are community benefits and participant privacy protected?
    response: Review the benefits and royalty agreement and study-specific governance before joining.

competitors

  • name: deCODE genetics
    why: Alternative population-genetics research using an Icelandic founder population.
  • name: Regeneron Genetics Center
    why: Another human genetics research organization supporting drug discovery.

keywords

  • human genetics drug discovery
  • genetically validated drug targets
  • founder population genomics
  • inherited disease genetics
  • clinical genomic partnerships
  • genetic biomarkers

voice

  • Science-led
  • Purpose-driven
  • Collaborative

signals

  • text: A pharma team is expanding human genetic validation of its discovery pipeline.
  • text: A research group is launching an inherited disease or family genetics collaboration.

pricing

model: unknown

motion

sales_led

channels

  • research partnerships
  • scientific publications

confidence

medium

Founders

  • name: Jeremy Grushcow
    title: Founder
    role: Founder
    bio: Ph.D. in Molecular Genetics and Cell Biology (University of Chicago, 2000); J.D. with Honors (University of Chicago Law School, 2003). Previously: CBO, Sequence Bio S19 (Raised >$10m; LOIs signed with Sema4, Helix and Biogen); EVP, Strategic Development, Antibe Therapeutics (International partnerships, public company financings and disclosures; preclinical through Phase 1 for a novel pain therapeutic) Best dog dad ever; 7 out of 10 human dad.
  • name: Chris Gardner
    title: Founder
    role: Founder

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